Table 2. Gene Ontology groups that are enriched for significant negative correlations with T1-w/T2-w ratio in cortex (AUROC < 0.5).

CC: cellular component; MF: molecular function; BP: biological process.

Name	Gene Count	AUROC	p	pfwer	Aspect	T1 AUROC	T2 AUROC
regulation of cellular amino acid metabolic process	55	0.265	1.78E-09	1.11E-05	BP	0.286	0.705
mitochondrial protein complex	118	0.347	1.05E-08	6.57E-05	CC	0.338	0.577
regulation of cellular amine metabolic process	71	0.305	1.37E-08	8.54E-05	BP	0.315	0.675
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	67	0.305	3.49E-08	0.000217	BP	0.317	0.669
peptidase complex	79	0.323	5.39E-08	0.000336	CC	0.345	0.642
cellular amine metabolic process	112	0.353	8.92E-08	0.000556	BP	0.362	0.635
endopeptidase complex	61	0.302	9.03E-08	0.000562	CC	0.326	0.657
structural constituent of ribosome	144	0.372	1.25E-07	0.000777	MF	0.355	0.571
proteasome complex	60	0.303	1.48E-07	0.000919	CC	0.328	0.656
inner mitochondrial membrane protein complex	100	0.351	2.81E-07	0.00175	CC	0.33	0.571
amine metabolic process	117	0.364	3.8E-07	0.00236	BP	0.375	0.626
ribosomal subunit	168	0.391	1.19E-06	0.00742	CC	0.384	0.556
mitochondrial membrane part	168	0.394	2.45E-06	0.0152	CC	0.397	0.546
negative regulation of cell cycle G2/M phase transition	75	0.349	6.62E-06	0.0412	BP	0.357	0.638
cellular response to zinc ion	17	0.184	6.66E-06	0.0414	BP	0.188	0.819