Fig. 2.

Insulin-mediated peripheral glucose uptake (a), suppression of endogenous glucose production (b) and suppression of lipolysis (c), calculated as percentage change from basal to the low- or high-dose insulin infusion. Differences in sample size from Table 2 are due to a small number of participants missing basal data owing to the administration of a sliding scale insulin infusion to achieve euglycaemia 5 mmol/l prior to beginning the clamp. Data are expressed as mean (SEM). Statistical significance between BAM and WEM was assessed using an independent sample Student’s t test; there were no significant differences between BAM and WEM