Fig. 4.
Influence of indomethacin (Indo) on IL-6 secretion by neutrophils and macrophages stimulated with BCM-72 h. Neutrophils (a) and macrophages (b) at 5 × 105/well were stimulated with BCM-72 h (20%) in the presence or absence of Indo (10 µM). IL-6 level was analyzed in supernatants collected from 24-h cell cultures by ELISA. φ—non-stimulated cells, expressed IL-6 release below 0.1 ng/ml. Data are mean ± SEM values of three independent experiments. Groups were run in triplicates. ***p < 0.001 for BCM-72 h vs. BCM-72 h + Indo, one-way ANOVA