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. 2019 Apr 5;9:5681. doi: 10.1038/s41598-019-42240-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Subgroup analyses of the primary outcome. The forest plot shows that the difference in the odds ratio for functional independence (defined as a modified Rankin Scale score of 0–2) at 3 months favored the blood pressure ≤ 130/80 mmHg group across all prespecified subgroups. NIHSS, National Institutes of Health Stroke Scale; IV, intravenous. Adjusted variables: age, sex, diabetes mellitus, dyslipidemia, atrial fibrillation, smoking, NIHSS score at 24 h, recanalization, and mechanical thrombectomy.