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. 2019 Apr 5;9:5662. doi: 10.1038/s41598-019-42076-2

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Antigen/vaccine structures and conjugation procedures used in this work. (A) structure of the 16-residue tandem repeat peptide from MUC4 with a TF_ag at position Ser5 (5TF_ag-TR_MUC4) and the PEG linker used to conjugate to gold nanoparticles to construct our vaccine platform (shown), as well as to prepare KLH and BSA conjugates (B).