Table 2.
Change in weight and body fat according to treatment.
| Probiotic (n = 30) | Placebo (n = 35) | Difference (p-value) | |||||
|---|---|---|---|---|---|---|---|
| Baseline | 3 months | *P | Baseline | 3 months | *P | ||
| Weight (kg) | 81.8 ± 13.6 | 81.2 ± 13.5 | 0.072 | 82.6 (79.3) | 83.4 (79.5) | 0.012 | −1.35 (0.0029) |
| BMI (kg/m2) | 30.0 ± 3.6 | 29.8 ± 3.6 | 0.047 | 30.1 (29.1) | 30.4 (28.8) | 0.024 | −0.48 (0.0024) |
| Visceral fat (cm2) | 146.1 (14.7) | 144.3 (14.4) | 0.730 | 158.35 ± 58.6 | 158.2 ± 59.5 | 0.992 | −169.5 (0.7590) |
| Total fat mass (kg) | 30.8(29.5) | 29.95 ± 6.4 | 0.104 | 31.0 (28.7) | 31.5 (30) | 0.07 | −1.25 (0.0282) |
| Total body fat (%) | 37.9 ± 6.7 | 37.1 ± 6.3 | 0.146 | 37.3 ± 7.53 | 37.7 ± 7.31 | 0.260 | −0.90 (0.0324) |
| Visceral fat grade | 14.0 ± 3.7 | 13.6 ± 3.4 | 0.192 | 14.3 ± 4.55 | 14.9 ± 4.8 | 0.092 | −1.12 (0.0297) |
| Right liver FF (%) | 17.3 (16.1) | 15.1 ± 7.7 | 0.053 | 14.7 (13.3) | 15.3 (12.8) | 0.272 | −2.63 (0.0284) |
| Left liver FF (%) | 15.2 (12.9) | 13.1 ± 7.9 | 0.019 | 13.1(10.0) | 13.6 (10.3) | 0.302 | −2.59 (0.0087) |
| Whole liver FF (%) | 16.3 (15.0) | 14.1 ± 7.7 | 0.032 | 13.9 (11.6) | 14.4 (11.5) | 0.255 | −2.61 (0.0129) |
| Waist-hip ratio | 0.94 ± 0.06 | 0.95 ± 0.05 | 0.239 | 0.96 ± 0.05 | 0.97 ± 0.06 | 0.113 | −0.001 (0.9317) |
| CAP (dB/m) | 313.4 ± 60.3 | 315.3 ± 42.3 | 0.859 | 310.0 ± 47.0 | 305.4 ± 47.0 | 0.569 | 5.69 (0.626) |
| Liver stiffness (kPa) | 9.65 ± 16.2 | 6.17 ± 2.50 | 0.221 | 6.76 ± 3.42 | 6.18 ± 2.88 | 0.142 | −3.39 (0.28) |
Data are expressed as median (interquartile range) with p values from Wilcoxon signed-rank test or mean difference with p value in parentheses.
BMI: body mass index, FF: fat fraction. Abdominal fat and visceral fat area were measured with magnetic resonance imaging. Total fat mass and total body fat were measured with bio-impedance. *p < 0.05 by paired t-test.