Table 5.

Changes in gut microbiome related to fatty liver decrease or increase by probiotic intervention.

	Decreased liver fat (FF ≤ −1.7%)										Increased liver fat (FF ≥ 1.7%)
	Probiotic Baseline		Probiotic 12 weeks		p value	Placebo Baseline		Placebo 12 weeks		p value	Probiotic Baseline		Probiotic 12 weeks		p value	Placebo Baseline		Placebo 12 weeks		p value
	Mean	SE	Mean	SE		Mean	SE	Mean	SE		Mean	SE	Mean	SE		Mean	SE	Mean	SE
Agathobaculum	564.8	319.9	2214	534.5	0.03	1844	1104	1899	1101	0.93	2380	1146	3167	1023	0.48	2662	1774	6520	2386	0.25
Dorea (OTU 527923)	587	119	1680	307.2	0.01	1186	487.3	1461	503.3	0.74	1306	572	2006	544.6	0.38	1201	641.5	3459	707.3	0.12
Dorea (OTU 195044)	363.1	60.67	760.1	127	0.01	560	145.4	660	237.3	0.68	725.5	91.93	1366	608.4	0.39	960.8	309.1	1327	405.3	0.52
Blautia	161.9	65.52	491.7	148	0.03	543.2	124.4	647.6	229.6	0.66	440.8	229.5	784	376.3	0.26	398	160.5	1598	611.4	0.02
Clostridium	148.9	57.16	381.4	149.3	0.20	72	24.16	625.4	148.1	0.02	323.5	314.5	2454	2300	0.44	134.8	47.21	1304	1274	0.41
Ruminococcus	55.8	13.9	345.3	98.52	0.01	256.6	98.44	158.6	61.83	0.27	241.3	124.6	627.8	251.3	0.16	88.5	42.85	248.5	85.52	0.03
Clostridium (OTU 363710)	76.9	19.7	152.6	50.82	0.22	43.2	15.3	239.2	41.95	0.01	345.5	216	998.3	906.7	0.44	52	18.69	458.5	428.9	0.40
Dorea (OTU 470168)	50.5	15.75	267.5	82.79	0.02	128.4	60.84	108.2	41.57	0.78	209	114.2	158	34.12	0.72	51.5	17.83	227.3	59.57	0.03

Data are expressed as mean with P values from paired t-test between 0 and 12-week samples. SE, standard error.