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. 2019 Apr 5;9:5695. doi: 10.1038/s41598-019-42131-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Nuclear Skp2 expression is associated with a high Gleason score in prostate cancer patients. (A) Patient samples from primary prostate carcinoma and benign hyperplasia were stained with anti-Skp2 antibody. Magnification: 40×. (B) Correlation of Skp2 with Gleason score. (C) Correlation of EMT-related marker (E-cadherin and vimentin) expression with Gleason score.