Fig. 2.

Effects of restless legs syndrome-associated SNPs on derived sleep traits. Presented are the effect estimates for genetic variants associated with a either L5 timing or sleep duration, b either sleep duration or the number of nocturnal sleep episodes, and c either L5 timing or sleep quality (number of nocturnal sleep episodes or sleep efficiency). Variants previously associated with restless legs syndrome are highlighted in red. Effect estimates represent standard deviations of the inverse-normal distribution of each trait. Error bars represent the 95% confidence intervals for each effect estimate