Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 5;9:5685. doi: 10.1038/s41598-019-42107-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Establishing the NB lincRNome. (a) Based on Ensembl annotation, a set of 3295 lincRNAs was robustly expressed in the SEQC dataset, whereas 3912 lincRNAs were found in the TARGET dataset. A total of 3290 lincRNAs were expressed in both groups. (b) Density distribution plots showing distances of chromatin marks and CAGE peaks to the TSS and expression levels, for protein coding genes and lincRNAs. (c) Percentages of the lincRNA derived read counts for the top 5 expressed lincRNAs for the SEQC and TARGET datasets. (d) Bar plot showing the number of specific lincRNAs per cancer type. (e) Expression pattern of a randomly selected neuroblastoma specific lincRNA lnc-FBX08-5 across the different cancer types. (f) Overlap of expressed lincRNAs between NB cell lines and SEQC. (g) Fischer exact-test p-values (non-adjusted) for lincRNAs that are only expressed in the SEQC dataset and are associated with stromal cell types according to FANTOM5. (Cancer type abbreviations: AML: Acute monocytic leukemia; BALL: B-cell Acute Lymphoblastic Leukemia; BLCA: Bladder Carcinoma; BRCA: Breast Carcinoma; CML: Chronic Myelogenous Leukemia; CRCA: Colon Adenocarcinoma; ESCC: Esophageal Squamous Cell Carcinoma; GBM: Glioblastoma; GCA: Gastric Carcinoma; HCC: Hepatocellular Carcinoma; HL: Hodgkin Lymphoma; HSNCC: Head and Neck Squamous Cell Carcinoma; LGG: Brain Lower Grade Glioma; MBM: Medulloblastoma; MEL: Melanoma; MESO: Mesothelioma; MM: Plasma cell myeloma; NB: Neuroblastoma; NHL: Non-Hodgkin Lymphoma; PACA: Pancreatic Adenocarcinoma; PRCA: Prostate carcinoma; RCC: Renal Cell Carcinoma; SCLC: Small Cell Lung Carcinoma; TALL: T-cell Acute Lymphoblastic Leukemia; THCA: Thyroid gland carcinoma.)