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. 2019 Apr 5;9:5685. doi: 10.1038/s41598-019-42107-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Altered expression levels of lincRNAs by copy number variations. Schematic representation of the number of cases with a copy number variation (1p deletion, 1q gain, 2p gain, 3p deletion, 11q deletion and 17q gain) present in our data set. The volcano plots show differentially expressed lincRNAs per copy number variation. Only 17q gain resulted in 5 robust significantly differentially expressed lincRNAs after iterative differential expression analysis (upregulated lincRNAs: lnc-BRC1-2, LINC02432, lnc-RPS6KA4-3; downregulated: LINC02211, LINC01930).