Table 1.
Some key FP receptor agonists and purported and bona fide FP receptor antagonists
| FP‐R agonist name | Structure |
|---|---|
| Cloprostenol |
|
| Fluprostenol (travoprost acid) |
|
| 16‐Phenoxy‐ω‐tetranor‐PGF2α |
|
| 17‐Phenyl‐ω‐trinor‐PGF2α (bimatoprost acid) |
|
| 13,14‐Dihydro‐17‐phenyl‐ω‐trinor‐PGF2α (latanoprost‐free acid) (PhXA85) |
|
| AFP‐172 (tafluprost acid) |
|
| AL‐12182 acid (AL‐12180) |
|
| FP receptor antagonists name | Structure |
|---|---|
| PGF2α dimethylamide |
|
| PGF2α dimethylamine |
|
| Phloretin |
|
| Glibenclamide |
|
| AL‐8810 |
|
| AL‐3138 |
|
| AS604872 |
|
| THG‐113.31; apparently equiv. to PDC31; a D‐oligopeptide of sequence D‐isoleucyl‐D‐leucylglycyl‐D‐histidyl‐N5‐(aminocarbonyl)‐D‐ornithyl‐D‐aspartyl‐D‐tyrosyl‐D‐lysine |
|
| PDC113.824 |
|
| AGN 211377 |
|
