Figure 1.

The overall structure of apo-AtMAPDA. (A) The structure shown in the ribbon rendition in the front and back views. The N- and C-termini were indicated and the secondary structure elements of AtMAPDA were labeled. The cyan dot indicated the zinc ion. (B) The close-up of the zinc-coordination state. The side chains of the key residues were shown as sticks and labeled. The two water molecules were the water for catalysis (Wcat) and coordination (Wcor) respectively, serving as the fifth and sixth ligands. The distances of the ligands from the metal were shown (units in Å).