Table 1.
Selected baseline characteristics of adults with dialysis-requiring acute kidney injury, stratified by renal recovery status
| Variablea | Overall |
Not recovered |
Recovered |
P |
|---|---|---|---|---|
| (N = 2214) | (n = 1309) | (n = 905) | ||
| Age, yr | 67.1 (13.1) | 67.9 (13.1) | 66.0 (13.1) | <0.001 |
| Women, n (%) | 904 (40.8) | 546 (41.7) | 358 (39.6) | 0.31 |
| Self-reported race, n (%) | 0.82 | |||
| White | 1195 (54.0) | 696 (53.2) | 499 (55.1) | |
| Black/African American | 281 (12.7) | 167 (12.8) | 114 (12.6) | |
| Asian/Pacific Islander | 268 (12.1) | 162 (12.4) | 106 (11.7) | |
| Other/Unknown | 470 (21.2) | 284 (21.7) | 186 (20.6) | |
| Hispanic ethnicity, n (%) | 408 (18.4) | 254 (19.4) | 154 (17.0) | 0.15 |
| Medical history, n (%) | ||||
| Acute myocardial infarction | 127 (5.7) | 83 (6.3) | 44 (4.9) | 0.14 |
| Coronary artery bypass graft surgery | 35 (1.6) | 19 (1.5) | 16 (1.8) | 0.56 |
| Stroke or transient ischemic attack | 90 (4.1) | 55 (4.2) | 35 (3.9) | 0.70 |
| Heart failure | 750 (33.9) | 495 (37.8) | 255 (28.2) | <0.001 |
| Diabetes mellitus | 1269 (57.3) | 770 (58.8) | 499 (55.1) | 0.08 |
| Hypertension | 1862 (84.1) | 1108 (84.6) | 754 (83.3) | 0.40 |
| Chronic liver disease | 181 (8.2) | 131 (10.0) | 50 (5.5) | <0.001 |
| Body mass index, kg/m2 | 31.3 (8.6) | 30.8 (8.5) | 32.1 (8.7) | <0.001 |
| Predicted probability of inpatient mortalityb | 0.1 (0.0) | 0.1 (0.0) | 0.1 (0.0) | 0.90 |
| Preadmission medication use, n (%) | ||||
| ACE inhibitor | 806 (36.4) | 455 (34.8) | 351 (38.8) | 0.05 |
| Angiotensin II receptor blocker | 384 (17.3) | 220 (16.8) | 164 (18.1) | 0.42 |
| Diuretic | 1403 (63.4) | 866 (66.2) | 537 (59.3) | 0.001 |
| Any antihypertensive agent | 1944 (87.8) | 1155 (88.2) | 789 (87.2) | 0.46 |
| Nonsteroidal anti-inflammatory drug | 186 (8.4) | 92 (7.0) | 94 (10.4) | 0.005 |
| Diabetic therapy | 823 (37.2) | 503 (38.4) | 320 (35.4) | 0.14 |
| Laboratory values | ||||
| Preadmission eGFR, ml/min per 1.73 m2 | ||||
| 60–150 | 777 (35.1) | 389 (29.7) | 388 (42.9) | <0.001 |
| 45–59 | 367 (16.6) | 190 (14.5) | 177 (19.6) | |
| 30–44 | 461 (20.8) | 277 (21.2) | 184 (20.3) | |
| 15–29 | 609 (27.5) | 453 (34.6) | 156 (17.2) | |
| Preadmission creatinine, mg/dl | 1.6 (0.8) | 1.7 (0.8) | 1.4 (0.7) | <0.001 |
| Median (25th–75th percentile) | 1.4 (1.0–2.1) | 1.5 (1.0–2.3) | 1.2 (1.0–1.8) | <0.001 |
| Preadmission dipstick proteinuria, n (%) | ||||
| Negative/Trace | 289 (13.1) | 164 (12.5) | 125 (13.8) | <0.001 |
| 1+ | 278 (12.6) | 170 (13.0) | 108 (11.9) | |
| ≥2+ | 457 (20.6) | 307 (23.5) | 150 (16.6) | |
| Unknown | 1190 (53.7) | 668 (51.0) | 522 (57.7) | |
| Preadmission hemoglobin, g/dl | 11.7 (2.0) | 11.5 (1.9) | 12.1 (2.1) | <0.001 |
| Preadmission serum albumin, g/dl | 3.6 (0.7) | 3.5 (0.7) | 3.7 (0.7) | <0.001 |
| Preadmission platelet count, × 103/μl | <0.001 | |||
| >400 | 108 (4.9) | 68 (5.2) | 40 (4.4) | |
| 150–400 | 1421 (64.2) | 823 (62.9) | 598 (66.1) | |
| <150 | 399 (18.0) | 270 (20.6) | 129 (14.3) | |
| Peak inpatient serum creatinine, mg/dl | 5.7 (2.8) | 5.6 (2.7) | 5.9 (2.9) | 0.02 |
ACE, angiotensin-converting enzyme; eGFR, estimated glomerular filtration rate.
a
Mean (SD) unless otherwise indicated.
b
Probability range 0 to 1.