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TEM immunogold labeling of Chymase in ACF rats. In 4 week (wk) ACF rat, immunogold labeling of chymase (black dots, arrowheads) at 20,000X (A and C; bar = 0.5 um) and 40,000X (B and D; bar = 0.25 um) indicating association with myofibrils between z-discs (arrows) and in mitochondria (mito). Panel D demonstrates chymase (black dots within boxes) in a cardiomyocyte nucleus.
