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. 2019 Apr 5;20:272. doi: 10.1186/s12864-019-5621-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Multiple sequence alignment of the chIFITM proteins showing the mutations across the samples. Amino acid sequence containing the chIFITM1,2,3 SNVs were aligned using Clustal Omega. IM1/2: intramembrane domain 1 and 2, CIL: conserved intracellular loop, *: silent SNVs. Red triangle: INDELs. Red circles highlight codons under positive selection, black circles codons under negative selection (Refer to Additional file 1: Table S4 for more details), black box: conserved localization signal, star: conserved lysine residues; yellow highlight: conserved double cysteine motif (CC)