Table 2.

Technical aspects of the included studies

Study, year	Image device	Injected dose	Time between injection and image acquisition	PET image analysis
Kole, 1998 [13]	PET	370 MBq	50 min	Visual
Schulte, 1999 [14]	PET	120–300 MBq	45–60 min	Visual and semiquantitative
Franzius, 2000 [15]	PET	3.7 MBq/kg	60 min	Visual and semiquantitative
Schulte, 2000 [16]	PET	120–300 MBq	45–60 min	Visual and semiquantitative
Franzius, 2001 [17]	PET	3.7 MBq/kg	60 min	Visual and semiquantitative
Franzius, 2002 [18]	PET	3.7 MBq/kg	60 min	Visual and semiquantitative
Yanagawa, 2003 [19]	PET	4.5 MBq/kg	50 min	Visual and semiquantitative
Kneisl, 2006 [20]	PET	444–740 MBq	60 min	Visual
Iagaru, 2006 [21]	PET/CT	151.7–721.5 MBq	60 min	Visual and semiquantitative
Volker, 2007 [22]	PET	NR	NR	Visual
Shin, 2008 [23]	PET/CT	8.14 MBq/kg	60 min	Visual and semiquantitative
Charest, 2009 [24]	PET/CT	379–500 MBq	60 min	Visual and semiquantitative
Hawkins, 2009 [25]	PET	259–370 MBq	45 min	Visual and semiquantitative
Benz, 2010 [26]	PET/CT	7.77 MBq/kg	60 min	Visual and semiquantitative
Lindholm, 2011 [27]	PET/CT	370 MBq	60 min	Visual and semiquantitative
Bandopadhyaya, 2012 [30]	PET/CT	370 MBq	60 min	Visual
Cistaro, 2012 [28]	PET/CT	120–277 MBq	60 min	Visual and semiquantitative
Ozkan, 2012 [29]	PET/CT	555 MBq	60 min	Visual and semiquantitative
Bai, 2013 [33]	PET/CT	3.5–5.7 MBq/kg	40–60 min	Visual and semiquantitative
Byun, 2013 [31]	PET/CT	7.4 MBq/kg or 370 MBq	60 min	Visual
Kong, 2013 [32]	PET/CT	8.14 MBq/kg	NR	Visual and semiquantitative
Chang, 2015 [35]	PET/CT	7.4 MBq/kg or 370 MBq	60 min	Visual and semiquantitative
Quartuccio, 2015 [34]	PET/CT	113–596 MBq	72 min	Visual
Hurley, 2016 [36]	PET/CT	5.55 MBq/kg	60 min	Visual and semiquantitative
Angelini, 2017 [38]	PET/CT	5.55 MBq/kg	NR	Visual and semiquantitative
Sharp, 2017 [37]	PET/CT	5.18 or 5.55 MBq/kg	60 min	Visual

NR not reported