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. 2019 Apr 5;19:328. doi: 10.1186/s12885-019-5550-3

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Heterogeneity index of 250 breast cancer tumors inferred from methylation profile obtained from TCGA dataset. a. Heat map showing the methylation status of 15 CpG sites (in rows) on 250 breast tumors (in columns). A color gradient from blue-white-red is used to represent low to high values of methylation (from 0 to 1). b. HI calculated for the 250 breast tumors represented in box plot graph