Missing outcome data balanced in numbers across intervention groups, with similar reasons for missing data across groups |
There is no quantitative measure of “balanced” |
For dichotomous outcome data, the proportion of missing outcomes compared with observed event risk not enough to have a clinically relevant impact on the intervention effect estimate |
There is no quantitative measure of “not enough” |
Missing data have been imputed using appropriate methods |
Not specified what is considered by Cochrane to be “appropriate methods” |
Reason for missing outcome data likely to be related to true outcome, with either imbalance in numbers or reasons for missing data across intervention groups |
There is no quantitative measure of “imbalance” |
Potentially inappropriate application of simple imputation. |
Not specified what is considered to be “inappropriate application” |