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. 2019 Mar 14;12(3):dmm037226. doi: 10.1242/dmm.037226

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© 2019. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — Analysis of mitochondrial ultrastructure and volume in mpv17^−/− and wild-type liver at 6 dpf. (A) TEM analysis of wild-type (a) and mpv17^−/− liver hepatocytes (b) (n=3). Scale bars: 2 µM. (B) Confocal images of double Tg(COXVIII-mls:EGFP); Tg(lfabp:dsRed) mpv17^+/? and mpv17^−/− siblings at 6 dpf (n=13) and 12 dpf (n=8). Scale bars: 50 µm. (C) Relative quantification of integrated density. Statistical analyses were performed using two-tailed Student's t-test. Statistical significance was evaluated by setting a confidence interval of 95%; data are mean±s.e.m. ns, not significant. Experiments were performed in biological replicates.