Table 1.
Characteristics of cases with acute pancreatitis and controls from 2000 to 2011
| Cases (N=1449) |
Controls (N=2479) |
||||
|---|---|---|---|---|---|
| Variable | n | (%) | n | (%) | p Value* |
| Sex | 0.89 | ||||
| Female | 549 | (37.9) | 945 | (38.1) | |
| Male | 900 | (62.1) | 1534 | (61.9) | |
| Age group (years) | 0.80 | ||||
| 20–39 | 159 | (11.0) | 257 | (10.4) | |
| 40–64 | 723 | (49.9) | 1234 | (49.8) | |
| 65–84 | 567 | (39.1) | 988 | (39.9) | |
| Age (years), mean (SD)† | 59.4 | (14.3) | 59.0 | (14.6) | 0.47 |
| Losartan | 0.75 | ||||
| Never use | 1300 | (89.7) | 2238 | (90.3) | |
| Current use | 52 | (3.6) | 90 | (3.6) | |
| Late use | 97 | (6.7) | 151 | (6.1) | |
| Other antihypertensive agents | 0.006 | ||||
| Never use | 81 | (5.59) | 197 | (7.95) | |
| Ever use | 1368 | (94.41) | 2282 | (92.05) | |
| Comorbidities before index date | |||||
| Alcohol-related disease | 154 | (10.6) | 191 | (7.70) | 0.002 |
| Biliary stone | 383 | (26.4) | 563 | (22.7) | 0.009 |
| Cardiovascular disease | 623 | (43.0) | 1048 | (42.3) | 0.66 |
| Chronic kidney disease | 93 | (6.42) | 100 | (4.03) | <0.001 |
| Chronic obstructive pulmonary disease | 364 | (25.1) | 596 | (24.0) | 0.45 |
| Diabetes mellitus | 367 | (25.3) | 567 | (22.9) | 0.08 |
| Hepatitis B | 68 | (4.69) | 55 | (2.22) | <0.001 |
| Hepatitis C | 58 | (4.00) | 45 | (1.82) | <0.001 |
| Hyperparathyroidism‡ | 7 | (0.48) | 1 | (0.04) | 0.005 |
| Hypertriglyceridaemia | 41 | (2.83) | 28 | (1.13) | <0.001 |
Data are presented as the number of subjects in each group with percentages given in parentheses, or mean with SD given in parentheses.
*χ2 test.
†t test comparing subjects with and without acute pancreatitis.
‡Fisher exact test.