Table 1.
Excipients used in glibenclamide formulations
| Formulation | |||
|---|---|---|---|
| Pharmaceutical | Functional | (% w/v) | |
| excipient | category | A | B |
| CMC sodium | Suspending agent | 0.80 | |
| Xanthan gum | Suspending agent | 0.20 | |
| Methylparaben | Antimicrobial preservative | 0.08 | 0.13 |
| Propylparaben | Antimicrobial preservative | 0.02 | 0.01 |
| Glycerin | Humectant | 5.00 | |
| Saccharine sodium | Sweetening agent | 0.20 | |
| Sorbitol 70% solution | Humectant and sweetening agent | 25.00 | |
| Citric acid anhydrous | pH regulator | 0.10 | |
| Propylene glycol | Cosolvent | 0.60 | |
| Distilled water | Vehicle | q.s. | q.s. |
CMC, carboxymethylcellulose; q.s., quantum satis—that is, the amount which is needed.