Table 3.
Stability of glibenclamide suspensions stored at 4, 25 and 40°C
| Time (days) | Suspension A | Suspension B | ||||
|---|---|---|---|---|---|---|
| 4°C | 25°C | 40°C | 4°C | 25°C | 40°C | |
| 0 | 100.1 (0.6) | 100.2 (0.8) | ||||
| 7 | 102.3 (0.9) | 100.5 (1.1) | 97.3 (1.7) | 99.4 (0.8) | 98.7 (1.6) | 95.1 (0.5) |
| 14 | 101.4 (0.6) | 102.5 (1.4) | 100.6 (0.3) | 100.8 (1.1) | 97.1 (2.5) | 95.7 (0.4) |
| 28 | 100.7 (1.2) | 94.7 (1.9) | 103.8 (1.5) | 101.6 (1.4) | 99.1 (1.1) | 94.9 (0.7) |
| 56 | 103.3 (2.1) | 97.6 (0.8) | 105.3 (0.8) | 104.2 (0.3) | 101.3 (1.2) | 96.9 (0.8) |
| 84 | 103.5 (0.7) | 99.1 (1.6) | 97.7 (1.0) | 98.8 (0.5) | 102.9 (0.5) | 94.9 (1.8) |
*Mean percentage of the initial glibenclamide concentration and relative standard deviation in parentheses (n=3).