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. 2016 Nov 7;24(6):355–360. doi: 10.1136/ejhpharm-2016-001087

Table 4.

Use of gastroprotection, transfusion requirements and length of hospitalisation with regard to gastropathy risk factors in patients admitted for non-steroidal anti-inflammatory drug (NSAID)-induced gastropathy

Risk factor Patients, n (%) Gastroprotection use, n (%) p Value Blood transfusion, n (%) p Value Mean (SD) hospital stay, days p Value
Age
 >60 years 37 (59.7) 18 (48.6) 0.001 21 (56.8) 0.026 6.1 (4.5) 0.022
 ≤60 years 25 (40.3) 2 (8.0) 7 (28.0) 4.1 (1.9)
Sex
 Men 32 (51.6) 8 (25.0) 0.207 16 (50.0) 0.429 5.9 (4.6) 0.145
 Women 30 (48.4) 12 (40.0) 12 (40.0) 4.5 (2.5)
Concomitant medication*
 Yes 24 (38.7) 13 (54.2) 0.003 14 (58.3) 0.098 5.6 (3.0) 0.548
 No 38 (61.3) 7 (18.4) 14 (36.8) 5.0 (4.2)
History†
 Yes 9 (14.5) 6 (66.7) 0.017 5 (55.5) 0.498 5.8 (2.9) 0.659
 No 53 (85.5) 14 (26.4) 23 (43.4) 5.2 (3.9)
Comorbidities‡
 Yes 15 (24.2) 9 (60.0) 0.008 12 (80.0) 0.002 7.2 (2.9) 0.021
 No 47 (75.8) 11 (23.4) 16 (34.0) 4.5 (3.8)

*Concomitant use of systemic corticosteroids, oral anticoagulants, clopidogrel or other NSAIDs (including ASA as antiplatelet).

†Personal medical history of peptic ulcer with/without complication (gastrointestinal bleeding, pyloric stenosis and perforation).

‡Cerebrovascular disease, chronic obstructive lung disease, cirrhosis, coronary disease, heart failure or renal failure.

ASA, acetylsalicylic acid.