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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Clin Toxicol (Phila). 2018 Oct 11;57(4):265–270. doi: 10.1080/15563650.2018.1511800

Table 2.

Physiological parameters at apnea between the swine treated with DMTS and saline contro

There is no significant difference in total dose of KCN, time to apnea, blood gases, or hemodynamics at apnea.

Control
n=6
DMTS
n=6
Difference between means 95% CI
difference
KCN mg/kg at apnea 1.08+0.15 1.02+0.09 −0.06+0.18 −0.47, 0.35
KCN mg/kg at treatment 1.95+0.31 1.90+0.19 −0.05+0.15 −0.38, 0.30
Time to apnea (minutes) 6.37+2.22 5.99+1.32 −0.38+1.053 −2.8, 2.04
Lactate (mmol/L) 2.41+1.26 1.78+ 0.53 −0.63+0.60 −2.18, 0.91
pH 7.37+0.03 7.35+0.03 −0.02+0.03 −0.07, 0.02
SBP (mmHg) 112+28.7 94+32.5 −17.5+17.7 −57.1, 22.1
MAP (mmHg) 78+23.9 70+27.7 −8.5+14.9 −41.9, 24.9
Pulse rate (beats per minute) 83+10.4 100+14 16.8+7.1 −0.8, 32.9

Data is presented as means + standard deviation.

KCN: potassium cyanide; mg/kg: milligram/kilogram; mmol: millimole; L: liter; mmHg: millimeters of mercury; CI: confidence interval; DMTS: dimethyl trisulfide