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Daily alcohol preference ratio of saline- or CFA-treated C57BL/6J mice over a 3-week continuous access regimen. Pain-related alcohol preference was assessed for (A) males (n = 8) and (B) females (n = 8) in 20 consecutive sessions. (C) Averages of daily intake were compared between saline- and CFA-treated males and females. Data are mean alcohol preference ± SEM. **** p < 0.0001 difference between groups.
