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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Alcohol. 2018 Oct 6;77:135–145. doi: 10.1016/j.alcohol.2018.10.002

Figure 6.

Figure 6.

Pain sensitivity of saline- and CFA-treated C57BL/6J mice was tested 24 hrs after last alcohol exposure. Using the Hargreaves test, paw withdrawal latency (s) was measured in response to a thermal nociceptive stimulus for substance-treated and untreated paws of (A) male and (B) female mice. Pain sensitivity was correlated with average daily alcohol intake in (C) males and (D) females. Data are mean paw withdrawal latency ± SEM. ** and **** correspond to p < 0.005 and p < 0.0001 difference between groups respectively.