Table 2.
Mean [11C]ABP688 BPND is higher in men than in women across the brain
| Region | Men, mean ± SD BPND |
Women, mean ± SD BPND |
% Difference (men > women) |
p-value |
|---|---|---|---|---|
| mPFC | 1.1 ± 0.26 | 0.94 ± 0.17 | 16% | 0.0097 |
| dlPFC | 1.0 ± 0.25 | 0.83 ± 0.16 | 20% | 0.0045 |
| OFC | 0.95 ± 0.22 | 0.78 ± 0.14 | 22% | 0.00093 |
| Associative striatum | 1.3 ± 0.22 | 1.1 ± 0.18 | 16% | 0.00068 |
| Sensorimotor striatum | 1.0 ± 0.18 | 0.86 ± 0.14 | 17% | 0.00016 |
| Ventral striatum | 1.4 ± 0.24 | 1.2 ± 0.18 | 17% | 0.00029 |
| Insula | 1.3 ± 0.21 | 1.1 ± 0.17 | 17% | 0.000081 |
| Hippocampus | 0.72 ± 0.18 | 0.64 ± 0.14 | 13% | 0.041 |
| Amygdala | 0.76 ± 0.18 | 0.69 ± 0.15 | 11% | 0.062 |
| Summary BP ND | 1.0 ± 0.20 | 0.89 ± 0.15 | 17% | 0.00037 |
mPFC, medial prefrontal cortex; dlPFC, dorsolateral prefrontal cortex; OFC, orbitofrontal cortex; p values from two-tailed t-tests. Summary BPND was computed as the unweighted mean of all regions