Table 1.

Investigated single nucleotide polymorphisms

Gene	rs number	Allele	Annotation	WT/WT	WT/var	Var/var	Missing	MAFa (%)	MAFb (%)
ABCG2	rs2231142	421C>A		75	18	1	0	11	9
ABCG2	rs2231137	34G>A		83	10	0	1	5	6
ABCB1	rs1045642	3435C>T		15	50	29	0	43	48
CYP3A4	rs35599367	15389C>T	*22	83	11	0	0	6	5

MAF minor allele frequency, var variant, WT wild type

^aMAF in this study

^bMAF in Europeans (obtained from the 1000 Genomes Project Phase 3 Browser at www.1000genomes.org on 26 March, 2018)