Table 2.
Semen Characteristics and Sperm Morphology in Chinese Men with Bi-allelic TTC21A Mutations
| Gene |
Subject |
|||
|---|---|---|---|---|
|
A004 IV-1 |
A015 II-1 |
S022 II-1 |
||
| TTC21A | TTC21A | TTC21A | ||
| Semen Parameters | ||||
| Semen volume (mL) | 4.6 | 3.4 | 3.8 | |
| Sperm concentration (106/mL) | 27.8 | 13.9 | 9.4 | |
| Motility (%) | 0.8 | 6.7 | 1.0 | |
| Progressive motility (%) | 0.0 | 1.7 | 0.0 | |
| Sperm Morphology | ||||
| Normal spermatozoa (%) | 0.0 | 0.0 | 0.0 | |
| Abnormal head-tail conjunction | Abnormal neck (%) | 46.5 | 23.0 | 45.9 |
| Absent head (%) | 0.5 | 0.5 | 1.3 | |
| Abnormal flagella | Short flagella (%) | 63.0 | 82.0 | 89.0 |
| Absent flagella (%) | 23.5 | 0.5 | 9.4 | |
| Coiled flagella (%) | 1.5 | 5.0 | 1.4 | |
| Angulation (%) | 2.5 | 1.0 | 0.0 | |
| Irregular caliber (%) | 5.5 | 2.0 | 0.0 | |