Skip to main content
. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Neuroimage. 2019 Feb 7;191:186–192. doi: 10.1016/j.neuroimage.2019.02.017

Figure 2. Lead-exposed and lead-naïve participant groups differences in neural connectivity between and across networks.

Figure 2.

Differences were observed in two network pairs. Bi-lateral connectivity across insular-temporal cortices showed greater increase with age in lead-naïve fetuses (panel B upper), whereas lead-exposed fetuses showed a strengthening of lateral prefrontal (SFG) to posterior cingulate (PCC) connectivity with age that was not present in the comparison group (panel B lower). Both observations suggest lack of advancement of typical processes with the same rate in lead-exposed fetuses, as cross-hemispheric increases and reduced PCC-SFG have been observed as normative fetal brain developmental processes (Jakab et al., 2014; Thomason et al., 2014).