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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Neuroimage. 2019 Feb 7;191:186–192. doi: 10.1016/j.neuroimage.2019.02.017

Table 2.

Age-related network change in each group

Lead exposed
positive
(%)		 negative
(%)		 total N Enrichment
χ2 		Enrichment
p-value		 McNemar
p-value
 CB - CB 95 5 20 8.79 0.050 0.787
 R pPar - R pPar 100 0 4 19.56 0.014 0.193
 PCC - R SFG 100 0 15 21.53 0.011 0.023*
 SC - L pIN/TPJ 43 57 14 10.65 0.038 0.405
Control
positive
(%)		 negative
(%)		 total N Enrichment
χ2 		Enrichment
p-value		 McNemar
p-value
 CB - CB 100 0 21 11.80 0.029 0.787
 R Temp - SMA 21 79 48 9.58 0.040 0.083
 R Temp - R pPar 0 100 10 8.42 0.048 0.154
 L pIN/TPJ - R Vis 40 60 20 13.16 0.024 0.099
 R Temp - SC 19 81 16 9.89 0.038 0.110
 R IN - CB 96 4 24 10.97 0.032 0.079
 R IN - L pIN/TPJ 80 20 15 8.66 0.046 0.031*

The number of significant connections within each network pair varies from region to region, and the proportion of those that are positive and negative also varies. Percentages denote proportion within each network pair that arose from significant positive or negative associations with age. ‘Total N’ denotes the number of total significant connections within each network pair. Enrichment χ2 statistics and p-values describe the degree to which the number of significant ROI-ROI pairs within each network pair was greater than could be expected by chance. McNemar p-values describe the statistical difference between lead exposed and control fetal ROI-ROI connectivity within each network pair.