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. 2018 Aug 10;68(8):1274–1281. doi: 10.1093/cid/ciy676

Figure 2.

Figure 2.

No association between microbial translocation and human immunodeficiency virus (HIV) persistence. A, Changes of microbial translocation markers. B, Pre– antiretroviral therapy (ART) levels of microbial translocation could not predict on-ART total HIV DNA. C, Microbial translocation markers were not associated with on-ART total HIV DNA. D, On-ART but not pre-ART sCD163 was associated with on-ART total HIV DNA. Microbial translocation markers were quantified in 64 patients with paired samples available both before and after ART. *P < .05, **P < .01, ***P < .001, ****P < .0001. Abbreviations: ART, antiretroviral therapy; EndoCAb, endogenous endotoxin-core antibody; HIV, human immunodeficiency virus; LBP, lipopolysaccharide-binding protein; LPS, lipopolysaccharide; PBMC, peripheral blood mononuclear cell; sCD14, soluble CD14; sCD163, soluble CD163; UC, human immunodeficiency virus–uninfected controls.