Table 3.

Factors Associated With High Total Human Immunodeficiency Virus DNA on Antiretroviral Therapy

Factor	Univariate Logistic Regression			Multivariate Logistic Regression
	OR	(95% CI)	P Value	OR	(95% CI)	P Value
Agea	1.00	(.97–1.03)	.994
Male sex	1.02	(.28–3.70)	.979
CD4 T-cell countb	0.74	(.59–.93)	.011
CD8 T-cell countb	1.07	(.99–1.16)	.075
CD4/CD8 ratioc	0.75	(.63–.90)	.002	0.75	(.62–.91)	.003
HIV RNAd	1.46	(.80–2.69)	.215
ART duratione	0.92	(.88–.97)	.001
On-ART CD4 T-cell countb	0.77	(.62–.95)	.015
On-ART CD8 T-cell countb	1.17	(1.04–1.32)	.011
On-ART CD4/CD8 ratioc	0.80	(.71–.91)	.001
On-ART IDO activityf	1.09	(1.04–1.13)	<.0001	1.09	(1.04–1.14)	<.0001

Abbreviations: ART, antiretroviral therapy; CI, confidence interval; HIV, human immunodeficiency virus; IDO, indoleamine 2,3-dioxygenase; OR, odds ratio.

^aShown per 1 year increase.

^bShown per 100 cells/μL increase.

^cShown per 0.1 increase.

^dShown per 1 log₁₀ copies/mL increase, data from 99 patients.

^eShown per 1 month increase.

^fShown per 1 nM/μM increase.