TABLE 1.
Baseline characteristics of patients
| f-IIP | p-value | IPF | f-NSIP | p-value | |||
| All | Mild-to-moderate | Severe | |||||
| Patients | 112 | 65 | 47 | 61 | 51 | ||
| Age years | 66.8±10.2 | 67.9±9.3 | 65.1±11.3 | 0.15 | 66.8±10.0 | 66.7±10.6 | 0.97 |
| Male/female | 70/42 | 41/24 | 29/18 | 0.88 | 46/15 | 24/27 | 0.002 |
| BMI kg·m−2 | 27.4±4.8 | 28.8±5.0 | 25.4±3.6 | <0.001 | 27.8±4.3 | 27.0±5.3 | 0.36 |
| FVC % pred | 69.7±19.7 | 78.6±17.1 | 57.4±16.2 | <0.001 | 68.6±18.0 | 71.1±21.6 | 0.52 |
| FEV1 % pred | 70.1±19.4 | 78.3±17.2 | 59.3±16.8 | <0.001 | 69.6±18.3 | 70.8±20.9 | 0.74 |
| TLC % pred | 67.6±15.2 | 73.8±15.0 | 58.7±10.4 | <0.001 | 66.7±14.4 | 68.7±16.2 | 0.55 |
| DLCO % pred | 35.9±12.7 | 42.4±10.3 | 23.9±6.5 | <0.001 | 33.4±9.8 | 39.1±15.1 | 0.033 |
| 6MWT distance m | 357±116 | 391±109 | 303±109 | <0.001 | 370±113 | 338±120 | 0.20 |
| 6MWT nadir SpO2 % | 83±7 | 86±6 | 80±7 | <0.001 | 82±7 | 86±7 | 0.011 |
| 6MST strokes | 364±150 | 413±151 | 292±116 | <0.001 | 371±144 | 356±157 | 0.63 |
| HADS score | 15.2±7.0 | 14.1±6.7 | 16.6±7.4 | 0.067 | 15.0±6.7 | 15.5±7.5 | 0.70 |
| VSRQ score | 37.3±16.4 | 40.8±15.0 | 32.3±17.1 | 0.007 | 37.6±16.4 | 36.9±16.5 | 0.82 |
Data are presented as n or mean±sd, unless otherwise stated. f-IIP: fibrosing idiopathic pulmonary pneumonia; IPF: idiopathic pulmonary fibrosis; f-NSIP: fibrotic nonspecific interstitial pneumonitis; BMI: body mass index; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; TLC: total lung capacity; DLCO: diffusing lung capacity of the lung for carbon monoxide; 6MWT: 6-min walk test; SpO2: arterial oxygen saturation measured by pulse oximetry; 6MST: 6-min stepper test; HADS: Hospital Anxiety and Depression Scale; VSRQ: Visual Simplified Respiratory Questionnaire.