Table 2.
Physical characteristics of Xenical and generic orlistat products, following removal from capsules
| Drug product | Description | Melting temperaturea, °C | Polymorphic crystalline form | Average fill massb, mg | Average orlistatc content, mg | |
|---|---|---|---|---|---|---|
| colour | appearance | |||||
| Xenical | white / off-white | pellets | 43.6 | B | 240.6 | 118.3 |
| Cobese | almost white | powder | 43.1 | A | 231.2 | 113.7 |
| Cuvarlix | off-white | highly agglomerated powder | 44.8 | A | 243.8 | 120.1 |
| Fingras | off-white | powder | 42.2 | B and A | 248.9 | 116.2 |
| Lesofat | off-white | pellets | 42.1 | A | 245.8 | 116.2 |
| Obelit | off-white | powder | NT | A | 260.6 | 114.6 |
| Xeniplus | off-white | powder | 42.2 | A | 252.3 | 117.8 |
| Xiluet | off-white | spheroids | NT | A and B | 332.1 | 116.9 |
| Xinplex | off-white | irregular balls | 41.1 | B (some A) | 244.7 | 114.1 |
| Zerocal | white | powder | NT | A | 184.4 | 126.4 |
NT = Not tested.
a
Specification 42–44 °C.
b
Specification 228.2–252.2 mg.
c
Specification 114.0–126.0 mg.