Table 2.
Metabolic complications Diabetes, insulin resistance Dyslipidaemia Metabolic syndrome Hyperuricaemia, gout Low-grade inflammation |
Cardiovascular disorders Hypertension Coronary heart disease (CHD) Congestive heart failure Stroke Venous thromboembolism |
Respiratory disease Asthma Hypoxemia Sleep apnoea syndrome Obesity hypoventilation syndrome (OHS) (Pickwickian syndrome) |
Cancers Oesophagus, small intestine, colon, rectum, liver, gallbladder, pancreas, kidney, leukaemia, multiple myeloma, and lymphoma In women: endometrial, cervix uteri, ovary, breast cancer after menopause In men: prostate |
Osteoarthritis (knee) and an increase in pain in the weight bearing joints |
Gastro intestinal Gallbladder disease Non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steato-hepatitis (NASH) Gastro-esophageal reflux Hernia |
Urinary incontinence |
Reproductive health Menstrual irregularity, infertility, hirsutism, polycystic ovaries Miscarriage Gestational diabetes, hypertension, preeclampsia, Macrosomia, foetal distress, malformation (i.e. neural tube defect) Dystocia and primary caesarean section |
Miscellaneous Idiopathic intracranial hypertension Proteinuria, nephrotic syndrome Skin infection Lymphoedema Complications from anaesthesia Periodontal disease |
Psychological and social consequences Low self-esteem Anxiety and depression Stigmatisation Discrimination in employment, college acceptance, job earning etc. |
The specific levels of risk associated with obesity vary with age, gender, ethnicity and social conditions.