Figure 3.

Phages escape strains with multiple spacers by deletions. (a) Schematic of the ϕTE tail fibre and (c) tape measure protein genes showing the regions targeted by different anti-ϕTE strains. (b,d) Diagrams of the deletion escape phages, showing the deleted regions (dashed bars), from 1×anti-ϕTE strains (light grey bars) and the 3×anti-ϕTE TFP strain (dark grey bars). The host strain (TE TFP/ TMP#), deletion size and escape phage number are shown for each phage mutant. Phage ϕTE35 (*) was isolated on two strains, TE TFP1 and 6. For further details, see electronic supplementary material, table S4.