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. 2019 Apr 8;219(Suppl 1):S30–S37. doi: 10.1093/infdis/jiy666

Figure 2.

Figure 2.

Sequence alignment of closely related influenza A virus strains. The sequences of influenza A viral proteins were aligned using CLC sequence Viewer 7.7 (Qiagen, Aarhus) to show sequence identity. HA alignments for H1N1 A/California/07/09 and H5N1 A/Vietnam/1203/04 (A) and H3N2 A/ New York/384/05 HA and H7N9 A/Anhui/1/2013 (B) are shown in pairs, based on the genetic relatedness. The sequence relatedness of NA (C) NP (D), M1 (E), and NS1 (F) are also shown where sequences from gene segments from 5 viruses (H1N1 A/Caledonia/20/99H1N1, A/California/07/09, H5N1 A/Vietnam/1203/04, H3N2 A/ New York/384/05, and H7N9 A/Anhui/1/2013) were aligned against each other. Dark gray segments represent sequence identity while light gray segments represent areas of any sequence disparity across the viral proteins that were compared. Abbreviations: HA, hemagglutinin; M1, matrix protein; NA, neuraminidase; NP, nucleoprotein; NS1, nonstructural protein.