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Common mechanisms and mediators in cancer and in atherosclerosis. Cancer and atherosclerosis share many common pathological mechanisms as depicted. Numerous mediators implicated in these two seemingly diverse diseases operate in both. FGF, fibroblast growth factor; MMP, matrix metalloproteinase; PDGF, platelet-derived growth factor; TGF-β, transforming growth factor beta; VEGF, vascular endothelial growth factor.
