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Regulation of cell accumulation in cancer and in atherosclerosis. The accumulation of cells in both cancer and atherosclerosis depends on the balance of growth stimulators and growth suppressors. In addition, some mediators promote cell death including programme cell death by apoptosis, and other pathways oppose cell death. The text and Figure 1 mention some of the mediators involved in regulating this balance between proliferation, cytostasis, and cell death.
