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. 2019 Feb 11;115(5):978–988. doi: 10.1093/cvr/cvz021

Figure 6.

Figure 6

MPs increases inflammatory markers expression via ETB and ETA receptors in HAEC. mRNA expression of TNF-α, IL-6, MCP-1, iNOS, COX-2, and VCAM-1 was determined by real-time PCR in HAEC exposed to total post-treatment MPs in presence or absence of BQ123 and BQ788 pre-incubated 30 min before the stimulation with MPs. PCR values were normalized by GAPDH mRNA expression (n = 6–12). Results are represented as mean ± SEM. Data were analysed using one-way ANOVA followed by a post hoc Tukey test. *P < 0.05 vs. NS; φP < 0.05 vs. post-treatment.