Fig. 5.

1810034E14Rik improved brain damage after 1 h MCAO/24 h reperfusion. a The expression of lncRNA-1810034E14Rik in the infarcted cortex at day 1, day 2, day 3, and day 7 was tested by RT-qPCR. b A 1810034E14Rik lentiviral vector expressing GFP was infected in the mice cortex by a stereotactic instrument. c The expression of 1810034E14Rik was examined by RT-qPCR in the cortex after injection. The neurological severity scores (d), rota-rod test (e), and grip strength (f) were performed to evaluate functional outcome after MCAO. g Brain water content was examined to measure brain edema severity. h, i Infarct volume after MCAO was confirmed by TTC staining. The data represents mean ± SEM. n = 15, *P < 0.05, **P < 0.01, and ***P < 0.001 versus the sham group; ^#P < 0.05 and ^##P < 0.01 versus the MCAO group