Table 3.
Differential expression of Vir genes in Saimiri and Aotus infection
| DESeq2 | edgeR | ||||
| Entrez gene | Description | Log2 fold change | Padj* | Log2 fold change | FDR |
| Saimiri P. vivax infection | |||||
| PVX_021680 | Variable surface protein Vir4 | 3.16 | 6.76E-03 | 2.443797 | 0.043963 |
| PVX_062690 | Variable surface protein Vir18 | 2.07 | 1.57E-02 | ||
| PVX_121855 | variable surface protein Vir18 | 1.90 | 1.99E-02 | 1.499001 | 0.02577 |
| Aotus P. vivax infection | |||||
| PVX_003485 | Variable surface protein Vir4 | −1.11 | 4.04E-02 | ||
| PVX_004539 | Variable surface protein Vir12-related | −1.15 | 4.84E-02 | ||
| PVX_104180 | Variable surface protein Vir12 | −1.24 | 3.37E-02 | ||
| PVX_097555 | Variable surface protein Vir12/16-related | −1.43 | 1.70E-02 | ||
| PVX_133260 | Variable surface protein Vir12, truncated | −1.46 | 3.17E-02 | ||
| PVX_094240 | Variable surface protein Vir12/24-related | −1.46 | 4.66E-02 | ||
| PVX_093710 | Variable surface protein Vir24-related | −1.47 | 4.38E-03 | −1.527948 | 0.006904 |
| PVX_088780 | Variable surface protein Vir24-related | −1.56 | 1.22E-02 | ||
| PVX_005580 | Variable surface protein Vir4 | −1.58 | 2.41E-02 | ||
| PVX_005060 | Variable surface protein Vir12-like | −1.65 | 1.29E-02 | −1.606289 | 0.025872 |
| PVX_115475 | Variable surface protein Vir14 | −1.74 | 4.75E-02 | ||
| PVX_097540 | Variable surface protein Vir24-related | −1.87 | 2.94E-03 | −2.105455 | 0.010348 |
| PVX_083575 | Variable surface protein Vir24-related | −1.90 | 3.29E-02 | ||
| PVX_101570 | Variable surface protein Vir5-related | −2.05 | 4.58E-02 | ||
| PVX_112645 | Variable surface protein Vir17-like | −2.52 | 4.91E-06 | −2.725464 | 8.33E-05 |
| PVX_003495 | Variable surface protein Vir22/24-related | −2.53 | 1.03E-03 | ||
| PVX_001615 | Variable surface protein Vir12/24-related | −2.99 | 1.72E-02 | ||
| PVX_102630 | Variable surface protein Vir27 | −3.11 | 4.40E-05 | −2.988085 | 0.00167 |
| PVX_102640 | Variable surface protein Vir12-related | −3.15 | 1.83E-02 | −3.271886 | 0.03084 |
| PVX_036190 | Variable surface protein Vir34 | −3.36 | 4.86E-02 | ||
| PVX_088790 | Variable surface protein Vir21-like | −3.40 | 2.43E-06 | ||
| PVX_088785 | Variable surface protein Vir12 | −3.44 | 4.91E-06 | ||
| PVX_105710 | Variable surface protein Vir1/9 | −4.54 | 1.03E-03 | −5.602723 | 0.001615 |
The table shows the number of P. vivax Vir genes that were up-regulated (positive) in Saimiri infection or up-regulated (negative) in Aotus infection with the log2 fold change by DESeq2 and edgeR analyses. Bold font indicates genes that were up-regulated above a log2 fold change cutoff of 2; italicized font indicates genes that were up-regulated above a log2 fold change cutoff of 1.
*
Genes with an adjusted P value (padj) < 0.05. FDR, false discovery rate.