Table 5.
Student’s t-test for HRQoL scores according to mIBI scores 0–1 vs 2–3.
| QoL variable | mIBI 0–1 | mIBI 2–3 | P-value |
|---|---|---|---|
| EORTC QLQ-C30 | |||
| C30 Physical functioning | 80.0 (19.8) | 63.6 (25.3) | <0.0001 |
| C30 Role functioning | 85.3 (25.1) | 63.5 (35.3) | <0.0001 |
| C30 Emotional functioning | 71.8 (23.5) | 68.9 (27.6) | 0.2329 |
| C30 Cognitive functioning | 79.1 (23.7) | 74.8 (25.4) | 0.0658 |
| C30 Social functioning | 76.2 (26.2) | 60.0 (32.2) | <0.0001 |
| C30 Global QoL | 58.9 (23.9) | 45.3 (27.2) | <0.0001 |
| C30 Fatigue | 33.4 (27.4) | 52.9 (29.1) | <0.0001 |
| C30 Nausea/vomiting | 6.1 (14.1) | 16.6 (26.1) | <0.0001 |
| C30 Pain | 24.7 (28.5) | 40.4 (32.8) | <0.0001 |
| C30 Dyspnoea | 24.6 (28.7) | 35.6 (33.1) | 0.0002 |
| C30 Insomnia | 35.7 (34.0) | 46.7 (37.1) | 0.0012 |
| C30 Appetite loss | 21.2 (30.3) | 43.9 (37.4) | <0.0001 |
| C30 Constipation | 16.0 (26.7) | 17.4 (26.8) | 0.5753 |
| C30 Diarrhea | 13.0 (23.2) | 19.6 (29.5) | 0.0094 |
| C30 Financial difficulty | 44.5 (36.3) | 58.7 (37.0) | <0.0001 |
| C30 Index-score | 24.5 (16.5) | 37.0 (20.4) | <0.0001 |
| EORTC QLQ-HCC18 | |||
| HCC18 Fatigue | 27.1 (22.1) | 43.4 (26.9) | <0.0001 |
| HCC18 Body image | 18.7 (20.2) | 32.6 (23.3) | <0.0001 |
| HCC18 Jaundice | 21.8 (20.2) | 25.4 (24.2) | 0.0840 |
| HCC18 Nutrition | 20.6 (18.0) | 34.0 (22.7) | <0.0001 |
| HCC18 Pain | 19.3 (21.9) | 27.8 (26.3) | 0.0003 |
| HCC18 Fever | 4.6 (12.9) | 8.3 (15.9) | 0.0065 |
| HCC18 Sex life | 24.7 (31.5) | 32.4 (37.1) | 0.0202 |
| HCC18 swelling | 22.0 (29.7) | 44.7 (36.9) | <0.0001 |
| HCC18 Index-score | 19.8 (14.6) | 31.1 (17.7) | <0.0001 |
Notes: Data are presented as mean (SD).
Abbreviations: EORTC, European Organization for Research and Treatment of Cancer; HCC, hepatocellular carcinoma; HRQoL, health-related quality of life; mIBI, modified inflammation-based index; QoL, quality of life.