Table 2:
Hepatocellular | Cholestatic/ mixed |
P-value** | Reference | |
---|---|---|---|---|
Statins |
n=14 153 (0 to 1866) |
n=8 153 (0 to 3600) |
p=0.913 | Russo et al.[38] |
Azithromycin |
n=10 20 (38 to 65) |
n=8 17 (2 to 38) |
p=0.887 | Martinez et al. [39] |
Cefazolin |
n=3 23 (21 to 23) |
n=16 20 (6 to 29) |
p=0.487 |
Alqahtani SA, et al.[40] |
Quinolones |
n=4 13 (5 to 27) |
n=8 2 (1 to 11) |
p=0.215 |
Orman ES, et al.[41] |
Cyproterone acetate (CPA) | n=20 150 (105 to 215) |
n=2 150 & 151 |
p=0.866 |
Bessone F, et al. [42] |
Ceftriaxone |
n=2 11 & 21 |
n=13 8 (4 to 14) |
p=0.229. |
Nakaharai K, et al. [43] |
Latency is measured in days from drug start to abnormal liver tests
p-value for hepatocellular injury versus cholestatic injury (defined as R value: ALT times upper limit of normal (ULN) / alkaline phosphatase times upper limit of normal (ULN).