| Number of | Percent with outcome | |||||
| Outcome | Studies | Participants | Gabapentin | Placebo | Risk ratio (95% CI) | NNT (95% CI) |
| Substantial benefit | ||||||
| At least 50% pain intensity reduction | 7 | 2031 | 33 | 19 | 1.7 (1.4 to 2.0) | 6.9 (5.5 to 9.4) |
| PGIC very much improved | 2 | 563 | 15 | 6 | 2.7 (1.5 to 4.8) | 11 (7.0 to 22) |
| Any definition of substantial benefit (at least 50% pain intensity reduction or PGIC very much improved) | 8 | 2260 | 32 | 17 | 1.8 (1.5 to 2.1) | 6.7 (5.4 to 8.7) |
| Moderate benefit | ||||||
| At least 30% pain intensity reduction | 2 | 529 | 54 | 38 | 1.4 (1.1 to 1.7) | 6.5 (4.0 to 16) |
| PGIC much or very much improved | 7 | 2013 | 39 | 29 | 1.3 (1.2 to 1.5) | 9.7 (6.9 to 16) |
| Any definition of moderate benefit (at least 25% pain intensity reduction or PGIC much or very much improved) | 8 | 2260 | 46 | 25 | 1.8 (1.6 to 2.0) | 4.8 (4.1 to 6.0) |
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