| 2005 review | 2011 update | 2014 Update | 2017 update | ||||
| Outcomes | Any improvement |
IMMPACT moderate benefit |
IMMPACT substantial benefit |
IMMPACT moderate benefit |
IMMPACT substantial benefit |
IMMPACT moderate benefit |
IMMPACT substantial benefit |
| All studies | 4.3 (3.5 to 5.7) | 5.8 (4.8 to 7.2) | 6.8 (5.6 to 8.7) | Not calculated in this review | Not calculated in this review | ||
| PHN | 3.9 (3.0 to 5.7) | 5.5 (4.3 to 7.7) | 7.5 (5.2 to 14) | 5.7 (4.6 to 7.5) | 6.8 (5.4 to 9.3) | 5 (5 to 6) | 7 (6 to 9) |
| PDN | 2.9 (2.2 to 4.3) | 8.1 (4.7 to 28) | 5.8 (4.3 to 9.0) | 6.6 (4.9 to 9.9) | 5.9 (4.6 to 8.3) | 7 (5 to 10) | 7 (5 to 10) |
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