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. 2017 Jun 9;2017(6):CD007938. doi: 10.1002/14651858.CD007938.pub4

Gong 2008.

Methods Multicentre, randomised, double‐blind, placebo‐controlled, parallel groups. No enrichment or imputation method mentioned
Forced titration from 300 mg daily to 1800 mg daily over 8 days, then stable dose to 6 weeks
Participants PHN
N = 231
Mean age 66 years (± 12), 43% women
Mean baseline PI: 6.2/10 (± 1.3)
Interventions Gabapentin 1800 mg daily, n = 109
Placebo, n = 106
Rescue medication: 2 x 100 mg tramadol if required 3 days after reaching maximum dose of gabapentin
Outcomes ≥ 25% and ≥ 50% pain relief
PGIC ("mild effective" and "excellent")
Sleep
Quality of life
Adverse events
Notes Oxford Quality Score: R = 1, DB = 2, W = 0, Total = 4
Unknown funding
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not adequately described. "Patients were randomised to different groups according to their recruitment order", but then refers to "pre‐determined code"
Allocation concealment (selection bias) Unclear risk Not adequately described. "Researchers allocated the treatments according to the pre‐determined code"
Blinding (performance bias and detection bias) 
 All outcomes Low risk "Identical‐appearing capsules containing placebo were used to blind the patients"
Incomplete outcome data (attrition bias) 
 Efficacy High risk Withdrawals (7%) and reasons for withdrawal not given per treatment group. No information about how data from withdrawals contributed to analyses
Size 
 Efficacy Unclear risk 50‐199 participants per treatment arm (106, 109)