Skip to main content
. 2017 Jun 9;2017(6):CD007938. doi: 10.1002/14651858.CD007938.pub4

Tai 2002.

Methods Randomised, double‐blind, placebo‐controlled, cross‐over, no enrichment. No imputation method mentioned
Titration to limit of tolerability or maximum 1800 mg over 3 weeks, then stable for remainder of 4‐week period; 2‐week washout then cross‐over
Participants Traumatic spinal cord injury > 30 days. PI before treatment > 4/10
N = 14 (7 participants with data)
Age 27‐48 years, 1/7 women
Interventions Gabapentin 1800 mg daily (max)
Placebo
NSAID, TCA and narcotics allowed for rescue medication as needed
Outcomes Withdrawals
Notes Oxford Quality Score: R = 2, DB = 2, W = 1, Total = 5
Grants from American Academy of Physical Medicine and Rehabilitation and Eastern Paralyzed Veterans Association
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Low risk Random distribution table
Allocation concealment (selection bias) Unclear risk Not reported
Blinding (performance bias and detection bias) 
 All outcomes Low risk Capsules with "identical shape and colour"
Incomplete outcome data (attrition bias) 
 Efficacy Unclear risk Imputation not mentioned
Size 
 Efficacy High risk < 50 participants per treatment arm (7/14 with data)